【摘要】 目的　获得一组正常新生儿和婴幼儿视觉、听觉同步诱发电位的实验室参考值 ,并讨论视听同步诱发电位的特点 ,初步探讨其作为新颖的电生理检查方法应用于新生儿 (婴幼儿 )听力和视力同步检查中的可行性。方法　应用视、听同步诱发电位技术对 19例足月正常新生儿 (日龄≤ 4d)和11例婴幼儿 (月龄在 1～ 5个月 )进行了检测 ,并与单独进行的听性脑干反应 (ABR)和闪光视觉诱发电位 (FVEP)进行了对比研究。结果　分别得到新生儿组和婴幼儿组视听同步诱发电位的波形结果 ,通过与单独进行的ABR、FVEP对比 ,发现FVEP对ABR的各波潜伏期值影响显著 (P <0 0 1) ,对ABR的波间期影响无显著性意义 (P >0 .0 5 ) ;ABR对FVEP的影响主要表现在新生儿组N2波潜伏期和婴幼儿组P1波潜伏期上 (P <0 .0 1)。结论　视听通路在中枢可能有联络神经元互通信息。视听同步诱发电位这种全新的电生理检测手段 ,势必为新生儿 (婴幼儿 )视听同步检查提供强有力的技术支持。更多还原

【Abstract】 Objective The purpose of this study is to bring out the consultable laboratory values of synchronous evoked potential in normal neonates and infants, investigate the characteristic of the electric response waveform, and explore its feasibility on applying to newborn auditory and visual function test as an electric physiology detection method. Methods It was applied to go on measuring 19 cases of mature normal neonate (≤4 days) and 11 cases of infants (≤5 months),also comparing with the study of ABRs, FVEPs independently. Results Get the electric response wave form results of synchronous electric evoked potential in both groups of newborn-infants, through comparing with the result of independent ABRs and FVEPs, the monitoring result demonstrated that there were an extreme significant changes of the corresponding parameters (wave Ⅰ,Ⅲ,Ⅴ latency )( P <0.01),and there were no significant changes of Ⅰ-Ⅲ,Ⅲ-Ⅴ interwave latency ( P >0.05);it also shows that ABRs impact on FVEPs in N2 wave latency of newborn group and P1 wave latency of infant group ( P <0.01). Conclusion Auditory and vision pathway may be had communicated information by the neuron in the center. The technology of the auditory and visual synchronous evoked potential brings out the whole new electric physiology detection tools, it will definitely offer powerful technical support in step for newborn-infant auditory and visual function test.更多还原