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硫普罗宁治疗老年人脂肪肝临床疗效观察

Tiopronin Zhusheye in treatment of the eldder patients with fattiness liver

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【作者】 苟师杨于艳秋

【Author】 Gou ShiYang,Yu YanQiu.Southeast university Affiliated Dongda Hospit al,Nanjing Jia ngSu 210018

【机构】 东南大学附属东大医院东南大学附属中大医院 210018南京

【摘要】 目的研究硫普罗宁治疗老年人脂肪肝和清除氧自由基的疗效。方法经CT证实的老年脂肪肝病人72例,分为2组。硫普罗宁36例,予硫普罗宁200mg,强力宁36例,予强力宁60mL,均溶于5%葡萄糖溶液250mL,ivdrip,qd,共四周。结果硫普罗宁与强力宁一样可以明显改善肝功能(P<0.05),硫普罗宁并有降低肝脏CT值(P<0.05),清除氧自由基的作用(P<0.01)。结论硫普罗宁治疗老年人脂肪肝疗效显著。

【Abstract】 Objective To observe clinical effects and against oxygen free radi cals of Tiopronin Zhusheye in the treatment of fattiness liver. Methods The pati ents(n=72)suffering from fattiness liver were divided into two groups. Thirty-s ix patients inTiopronin group were injected with Tiopronin Zhusheye 200 mg in 5 %glucose 250mL,iv drip, qd for 4 weeks as a course, while thirty six patients in control group were injected with Qianglining Zhusheye in the same way. Result s Tiopronin group may improve liver ability as same as control group, respective ly. There was no significant difference between the two groups(P>0.05). Tioproni n group was significant differencein patients with decrease liver CT(P<0.05) and against oxygen free radicals(P<0.01). Both groups had not severe adverse reacti ons. Conclusion Tiopronin Zhusheye is effective in treating elder fattiness live r patients

  • 【文献出处】 中国航天医药杂志 ,Medical Journal of Casc , 编辑部邮箱 ,2003年03期
  • 【分类号】R575.5
  • 【下载频次】36
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