【摘要】 目的　探讨并重新评价烧伤创面脓毒症与组织细菌定量的关系 ,将其进行临床分期。　方法　对近 5年符合条件的 32例烧伤患者进行组织细菌检查和定量分析 ,结合临床表现对创面脓毒症进行分期。　结果　 (1) 32例患者的 12 3个组织标本中 ,均可见到细菌侵入 ,有 82个标本的每克痂下组织菌量≥ 1× 10 5,4 1个标本的每克痂下组织菌量 <1× 10 5。其中 18例患者 6 8个标本 ,每克痂下组织菌量全部≥ 1× 10 5;5例患者 2 0个标本 ,每克痂下组织菌量全部 <1× 10 5;其余 9例患者的标本中仅部分每克痂下组织菌量≥ 1× 10 5。 (2 )根据细菌学结果并结合临床表现 ,可将创面脓毒症分为Ⅰ～Ⅳ期。　结论　 (1)临床有中毒表现并获得细菌侵入活组织的证据时 ,创面脓毒症的诊断即可成立。 (2 )将创面脓毒症分为IV期 ,有助于规范临床诊断、指导临床治疗更多还原

【Abstract】 Objective To investigate and re-evaluate the relationship between burn wound sepsis and tissue bacterial quantity. Methods Thirty-two patients admitted during past 5 years were enrolled in the study. Bacterial isolation and quantity in burn wound tissue were carried out. Meanwhile clinical signs were evaluated for the staging of burn wound sepsis. Results 1) Bacterial invasion could be identified in 123 pieces of tissue samples from 32 patients. Samples with tissue bacterial quantity≥ 10 5/g were found in 82 subeschar tissue samples, and 41 samples with bacteria<10 5/g. Subeschar tissue samples with bacterial quantity ≥ 10 5/g could be determined in 68 samples from 18 patients , and <10 5/g in 20 samples from 5 cases. In addition, samples of subeschar tissue with bacterial quantity≥ 10 5/g could only be found in some of the samples form 9 cases. 2) Burn wound sepsis could be classified intoⅠ-Ⅳ stages according to tissue bacterial quantification and clinical signs. Conclusion Burn wound sepsis could be established by identification of bacterial invasion into living tissue with clinical symptoms of toxemia.更多还原