【摘要】 目的探讨胰腺癌各种诊断方法的价值 ,以求进一步改善胰腺癌患者的预后。方法回顾分析 1990年 1月至 2 0 0 0年 12月收治的 32 1例胰腺癌患者的临床资料 ,统计患者的首发症状及各种检查方法的阳性例数。结果胰头癌、胰体尾癌和全胰癌最常见的首发症状为上腹痛 (分别占5 5 6 %、81 0 %、87 5 % )、腹胀不适 (2 7 8%、39 2 %、5 0 0 % )。CA19 9的阳性率达到 89 7%。影像学检查阳性率依次为核磁共振 (92 0 % )、血管造影 (91 7% )、CT(84 3% )、B超 (80 1% )、胃肠X线造影 (46 7% )。结论上腹痛、腹胀不适为胰头癌、胰体尾癌和全胰癌最常见的首发症状 ;CA19 9可为胰腺癌的确诊提供有价值的线索 ;所有 4 0岁以上有上腹痛及腹胀不适的患者均应行B超检查以排除胰腺癌 ;对临床上怀疑胰腺癌的患者应常规行CT检查。更多还原

【Abstract】 Objective This single-institution study was to evaluate various diagnostic means for patients with pancreatic cancer. Methods Three hundred and twenty-one patients with pancreatic cancer admitted into our hospital between Jan. 1990 and Dec. 2000 were enrolled, and the clinical data were analyzed retrospectively. Results The most common symptoms of patients with cancer in the head, body and tail and whole pancreas were abdominal pain (55.6%,81.0%,87.5%,respectively) and flatulance (27.8%,39.2%,50.0%,respectively).CA 19-9 was positive in 89.7% of all cases. The positive rate of image examination was 92.0% with MRI, 91.7% with angiography, 84.3% with CT, 80.1% with B ultrasound and 46.7% with GI series. Conclusions Abdominal pain and fullness are the most common symptoms for patients with cancer in the head, body and tail and whole pancreas.CA 19-9 testing presents valuable clues for the diagnosis of pancreatic cancer. All patients aged above 40 who seek medical advice for abdominal pain and flatulance should undergo ultrasound examination and CT scanning.更多还原