节点文献
替莫唑胺多晶型的制备及其热稳定性
Preparation and Thermostability of Polymorphs of Temozolomide
【摘要】 替莫唑胺在不同条件下进行了重结晶 ,经熔点、红外光谱、差热分析和粉末 X-射线衍射法鉴定 ,确认替莫唑胺存在 A、B两种晶型和一种粒状固体 C,采用差热分析法对 A、B和 C的热稳定性进行了测定和比较。
【Abstract】 The polymorphs A and B as well as a granular solid C of temozolomide were prepared by recrystallization from different solvents. Their characteristics were discussed by means of melting point, infrared spectrophotometry and X\|ray. In addition, the thermostability of A, B and C was studied by the differential scanning calorimetry.
- 【文献出处】 中国医药工业杂志 ,Chinese Journal of Pharmaceuticals , 编辑部邮箱 ,2003年04期
- 【分类号】TQ464
- 【被引频次】15
- 【下载频次】475