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幽门螺杆菌阴性慢性浅表性胃炎与功能性消化不良

Relationship between Helicobacter pylori negative chronic superficial gastritis and functional dyspepsia:are they the same disease?

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【作者】 罗政仁姒健敏王建国

【Author】 LUO Zheng-ren, SI Jian-min, WANG Jian-guo. Zhejiang University Gastroenterology Institution ,Sir RunRun Shaw Hospital, Hangzhou 310016, China

【机构】 浙江大学邵逸夫临床医学研究所胃肠疾病实验室浙江大学邵逸夫临床医学研究所胃肠疾病实验室 310016杭州现在湖南邵阳市中心医院消化内科422000310016杭州

【摘要】 目的 从治疗学的角度研究幽门螺杆菌 (Hp)阴性慢性浅表性胃炎 (CSG)与功能性消化不良 (FD)的关系。方法 将Hp阴性CSG患者 2 14例随机分成自身交叉治疗组和病例对照试验治疗组 ,用常用的慢性胃炎治疗方案 (甲方案 )和FD治疗方案 (乙方案 )进行自身交叉试验和病例对照试验 ,比较甲方案和乙方案的疗效。结果 在病例对照试验中 ,甲和乙方案的总有效率分别为89 2 %和 88 5 % ;在自身交叉试验中 ,甲和乙方案的总有效率分别为 81 8%和 89 8% ,甲方案和乙方案疗效比较差异无显著性 (P >0 0 5 )。结论 Hp阴性CSG与FD密切相关 ,二者可能是相同范畴的疾病。

【Abstract】 Objective To discriminate between Helicobacter pylori (Hp) negative chronic superficial gastritis and functional dyspepsia(FD) from therapeutic point of view.Methods 214 patients with Hp negative chronic superficial gastritis were randomly assigned into two groups.One group was case control trial group,another was cross-treated self-control group. Ordinary treatment of chronic gastritis (plan A)and FD plan(plan B)were given . Symptoms and pathologic changes were analysed and compared. Results In the case control group,the total effective rate of plan A and plan B was 89.2% and 88.5% respectively;in the cross-treated self-control group , the total effective rate of plan A and plan B was 81.8% and 89.8% respectively; There was no significant difference in the effective rate of the two different plans ( P >0.05). Conclusions Hp negative chronic superficial gastritis is similar to FD from therapeutic point of view.The method of treatment of the two dieases may be same, though they are named differently.

【关键词】 螺杆菌,幽门胃炎功能性消化不良
【Key words】 Helicobacter pyloriGastritisDyspepsia
  • 【文献出处】 中华内科杂志 ,Chinese Journal of Internal Medicine , 编辑部邮箱 ,2003年07期
  • 【分类号】R573.31;R574
  • 【被引频次】13
  • 【下载频次】153
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