【摘要】 目的分析冠状动脉 (CA)病变与室壁运动功能及心率变异 (HRV)的关系 ,探讨侧支循环对CA病变与室壁运动功能及心率变异 (HRV)之间关系的影响。方法对 93例CA病变 (狭窄≥ 70 % )患者作Leaman记分 ,左室壁运动功能作Cortina记分和HRV时阈分析。结果全组 93例中CA记分与左室壁运动功能记分呈弱相关 (r =0 .2 6 ,P <0 .0 5 )。在NCC组中 ,CA记分与左室壁运动功能记分呈密切正相关 (r=0 .5 4 ,P <0 .0 1)。全组 93例的CA记分与HRV各项指标无相关。而在NCC组中 ,CA记分与HRV的SDNN、DNNI、rMSSD和PNN 5 0呈负相关 (r分别为 - 0 .4 5 ,- 0 .4 2 ,- 0 .34和 - 0 .33,P <0 .0 1或 0 .0 5 )。结论CA的病变程度与左室壁运动功能及HRV的关系取决于病变的CA有无侧支循环 ,而侧支循环对CA病变患者的左室壁运动功能和心脏自主神经功能有保护作用。更多还原

【Abstract】 Objective To analyze the relationship between the severity of coronary lesions with left ventricular wall motion and heart rate variability(HRV) , and to explore the effect of collateral circulation on the relationship between coronary artery(CA) and HRV. Methods 93 CA patients(stenoses>70%) was scored by Leaman. The left ventricular wall motion function was assessed by Cortina score and HRV anlysis.Results In 93 cases, CA scoring was weakly correlated with left ventricular wall motion function(r=0.26,P<0.05), which was closely positively correlated with left ventricular wall motion in NCC group(r=0.54,P<0.01). CA scoring in 93 cases was not correlated with HRV. However, in NCC group, CA scoring was negatively correlated with SDNN, DNNI, rMSSD and PNN50 of HRV(r=-0.45, -0.42, -0.34 and -0.33, P<0.01 or 0.05). Conclusion The relationship between the severity of CA with left ventricular wall motion and HRV depends on whether the patients have collateral circulation, which plays an important protective role in the left ventricular wall motion and cardiac autonomotropic function of patients with coronary artery disease.更多还原