【摘要】 目的　探讨氯沙坦肾显像对肾血管性高血压的诊断价值。方法　 4 6例疑为肾血管性高血压患者 ,基础肾显像后均进行开博通和氯沙坦肾显像 ,并于肾显像后 7d内行肾动脉造影检查。结果　开博通肾显像和氯沙坦肾显像对肾血管性高血压诊断的灵敏度分别为 6 0 .0 %和 84 .0 % ,特异性分别为 95 .5 %和 97.0 % ,准确性分别为 85 .8%和 93.4 % ,阳性预测值分别为 83.3%和 91.3% ,阴性预测值分别为 86 .4 %和 94 .2 % ,两组比较 ,灵敏度和准确性差异有显著性 (P <0 .0 5 ) ,余指标差异无显著性。结论　氯沙坦肾显像对肾血管性高血压诊断的灵敏度和准确性明显高于开博通肾显像更多还原

【Abstract】 Objective To compare the value of captopril renography and losartan renography in identification of renovascular hypertension. Methods Forty six patients with suspected renovascular hypertension underwent radionuclide renography intervened with captopril at first and losartan in 24～48 h. All patients had renal artery angiography within 7 d after radionuclide renography. Results The sensitivity of captopril and losartan renography for diagnosing renovascular hypertension was 60.0% and 84.0%, and the specificity was 95.5% and 97 0%, respectively; the positive predictive rate was 83.3% and 91.3%, respectively; the negative predictive rate was 86.4% and 94.2%, respectively; the accuracy was 85.8% and 93.4%, respectively. The difference of sensitivity and accuracy between the two intervention agents was significant( P <0.05).But the difference of specificity between the two intervention agents was not significant ( P >0.05). Conclusion The sensitivity and accuracy of renoimaging intervened with losartan is evidently higher than that of captopril intervened imaging in diagnosis of renovascular hypertension.更多还原