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Cox回归分析对肝肾综合征预后因素的评估
Cox regression analysis of predictive factors of hepatorenal syndrome
【摘要】 目的 探讨影响肝肾综合征(HRS)预后的参数及最佳预后指标。方法 对71例肝硬化合并HRS患者进行研究,以确诊HRS时间为基线,选择35个可能对肝肾综合征预后产生影响的临床及生物化学指标,通过COX比例风险模型对患者预后进行多因素分析。结果 Child-Pugh评分是HRS的独立危险因素,相对危险度=1.333,95%可信区间为(1.026,1.731)。结论 Child-Pugh评分是临床上判断HRS患者预后的最重要指标。
【Abstract】 Objective To investigate the predictive factors and the best prognostic parameter of hepatorenal syndrome (HRS). Methods 71 patients with cirrhosis who underwent HRS were included for multivariate Cox regression analysis. 35 possible predictive factors that included clinical and biochemical features contributing to the survival of these patients were analyzed. Results Only Child-Pugh’s score at the time of diagnosis was the only dependent risk factor of HRS, RR=1.333, 95% CI (1.026, 1.731). Conclusion Child-Pugh’s score at the time of diagnosis of HRS is the best parameter for predicting the clinical outcome of HRS.
- 【文献出处】 中华肝脏病杂志 ,Chinese Journal of Hepatology , 编辑部邮箱 ,2003年10期
- 【分类号】R575
- 【被引频次】9
- 【下载频次】176