【摘要】 目的　探讨经皮穿刺O2 O3 混合气体注射术对腰椎间盘突出症的疗效及安全性。方法12 9例患者经CT或MR检查证实为腰椎间盘突出症 ,均表现为腰背痛及下肢麻痛。其中间盘膨出47例 ,突出 78例 ,脱垂 4例。在透视监视下采用 19～ 2 1G穿刺针经皮穿刺至腰椎间盘 ,实施盘内及椎旁间隙O2 O3 混合气体注射术。盘内注射 5ml,椎旁间隙注射 10～ 15ml ,O3 浓度为 40 μg/ml。 结果　随访 3～ 18个月 ,总有效率为 76.0 %。显效 79例 ( 61.2 % ) ,有效 19例 ( 14 .7% ) ,无效 3 1例( 2 4 0 % ) ,无任何严重并发症发生。结论　经皮穿刺O2 O3 混合气体注射术是治疗腰椎间盘突出症的1种安全、有效的方法更多还原

【Abstract】 Objective To evaluate the therapeutic effect and safety for the treatment of lumbar disc herniation by using intradiscal and paraspinal space injection of O 2-O 3 mixture. Methods One hundred and twenty-nine patients were selected in this study. All patients presented the symptoms of sciatica and low back pain. The diagnosis of the lumbar disc herniation including 47 bulging, 78 protrusion, and 4 extrusion was verified by CT or MR imaging. One hundred and eighty-nine herniated discs were chosen as therapeutic targets. O 2-O 3 mixture at 40 μg/ml and 19-21G puncture needles were prepared. The injection was conducted through the puncture of intradiscal and paraspinal space. For each herniated disc treatment, 5 ml O 2-O 3 mixture were injected into the intradiscal space and 10-15 ml into paraspinal space. Results The patients were followed up from 3 to 18 months after treatment. The therapeutic effect showed that 79 patients (61.2%) had excellent recovery, 19 cases (14.7%) had significant relief of symptoms, and 31 patients (24.0%) got failure in treatment. No serious complication occurred. Conclusion The therapeutic method of O 2-O 3 mixture injection into the lumbar intradiscal and paraspinal space was a safe and effective method for the treatment of the lumbar disc herniation.更多还原