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骨肉瘤的远处骨转移(附5例报告)

Distant Bone Metastasis of Osteosarcoma:A Report of 5 Cases

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【作者】 邢汝维宋金纲马育林滕胜

【Author】 Xing Ruwei Song Jingang Ma Yulin et al Department of Bone&Soft Tissue Tumour,Tianjin Cancer Hospital,Tianjin

【机构】 天津医科大学附属肿瘤医院骨软科天津医科大学附属肿瘤医院骨软科 天津市300060天津市300060天津市300060

【摘要】 目的:探讨骨肉瘤远处骨转移的临床表现,诊治过程及预后情况。方法:对我科1993年6月~1999年9月收治的5例骨肉瘤发生远处骨转移患者进行回顾性分析总结。结果:5例中3例为多发骨转移灶,2例为单发骨转移灶;4例合并肺转移,1例合并淋巴结、心包转移。经随访4~36个月,平均15.4个月,4例死亡,1例生存。结论:骨肉瘤的远处骨转移均为超关节的血行转移,两处以上骨转移灶者的生存期低于单发骨转移灶者,合并其它脏器转移者预后更差。化疗加适宜的手术是治疗此类患者较有效的方法。

【Abstract】 Objective:To explore the clinical manifestation,diagnosis,treatment and prog-nosis of distant bone metastasis of osteosarcoma.Methods:A retrospective analysis and study on five patients with distant bone metastasis of osteosarcoma treated in our department from1993.6to1999.9was carried out.Results:Of the five patients,three patients had multiple bone metas-tasis sites,respectively two patients with single bone metastasis site.Four patients were associated with lung metastasis,one of them had lymphnode and pericardium metastasis simultaneously.The mean of follow-up was15.4months,ranging from4months to36months.Four patients died and one alive.Conclusion:The distant metastasis of osteosarcoma is ultra-articular blood metastasis.The patient ’s survival with multiple metastasis sites(≥2)is less than those with single metastasis site,which associated with viscera metastasis had worse prognosis.Chemotherapy com bined with opera tion were effective.

  • 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,2003年11期
  • 【分类号】R738.1
  • 【下载频次】78
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