【摘要】 目的 :制备左旋卡尼汀氯化钠注射液 ,并对其质量进行控制。方法 :采用高效液相色谱法测定左旋卡尼汀含量 ,银量法测定氯化钠含量。结果 :左旋卡尼汀在0 90～4 00mg/ml浓度范围内线性关系良好 ,平均回收率为99 52% ,RSD=1 12%(n=9) ;氯化钠平均回收率为99 23% ,RSD=1 10 %(n=9)。结论 :左旋卡尼汀氯化钠注射液制备工艺简便 ,质控方法可行。更多还原

【Abstract】 OBJECTIVE:To prepare levocarnitine and sodium chloride injection and control its quality METHODS:The content of levocarnitine was determined by HPLC method and the content of sodiun chloride was determined by titrimeˉtry.RESULTS:Linear relationship was found in the levocarnitine concentrations ranging from0.90mg/ml to4.00mg/ml.The average recovery of levocarnitine was99.52%,RSD=1.12%(n=9);The average recovery of sodium chloride was99.23%,RSD=1.10%(n=9).CONCLUSION:Levocarnitine and sodium chloride injection is simple in preparation technique,feasible in quality control.更多还原