【摘要】 观察不同温度超声消融肺静脉口对电传导的影响 ,探索适合肺静脉口的最佳超声消融温度。选用健康成年犬 15只 ,随机分为 5 0℃、5 5℃及 6 0℃消融组 ,用特制的超声球囊导管在S1S1快速起搏下环状消融肺静脉口 ,观察产生电隔离的时间及消融后每隔 10min再次快速起搏观察电隔离是否存在。结果 :共消融肺静脉口 5 1个 ,实验发现 ,在消融温度为 5 0℃时 ,所有消融处均未产生电隔离 ;在消融温度为 5 5℃时多产生一过性电隔离 ;在消融温度为6 0℃时可产生有效电隔离消融温度为 6 0℃时 ,电隔离多发生在达到预设消融温度后 10s内 ,最长发生在达到预设消融温度后 2 2s。结论 :经球囊超声消融肺静脉口 ,在消融温度达到 6 0℃ ,持续 30s能够产生有效电隔离。更多还原

【Abstract】 To explore the best ablative temperature of getting effectively electrical isolation, the orifice of pulmonary vein of fifteen mongrel dogs were ablated with through the balloon ultrasound ablation (TTB-USA) system.Predetermined temperature at 50℃,55℃,60℃ respectively,ablative time: 60 seconds. Then observed the effect of TTB-USA on electrical isolation with different ablative temperature.Results:It could not reach electrical isolation at 50℃,and get temporary electrical isolation at 55℃,almost all pulmonary veins arrive at electrical isolation within 10 seconds at 60℃,the longest eletrical isolation occurred at 22 seconds later after ablation.Conclusion: Keeping 60℃ for 30 seconds could get effectively electrical isolation on orifice of pulmonary vein.更多还原