【摘要】 目的　研究凝血酶原基因 2 0 2 10G→A突变与中国人群脑血栓形成的关系。方法　应用PCR RFLP分析方法 ,检测了 80名脑血栓患者和 80名健康对照者的凝血酶原基因 2 0 2 10位的突变情况。结果　在所有研究对象中均未发现凝血酶原基因 2 0 2 10G→A突变。结论　中国人群凝血酶原 2 0 2 10A等位基因频率极低 ,2 0 2 10G→A突变不是中国人群脑血栓形成的危险因子。更多还原

【Abstract】 Objective To investigate the relation between prothrombin gene nutation (Thrombosis 20210 A allele) and cerebral thrombosis in Chinese. Methods Using PCR-RFLP assay , we determined 80 patients with cerebral thrombosis and 80 healthy controls for the prothrombin gene 20210 G→A. Results In all subjects, no promthrombin gene 20210G→A was detected. Conclusion The variant of prothrombin 20210G→A is low in Chinese , and the mutation is not the risk factor in Chinese cerebral thrombosis.更多还原