【摘要】 肥胖基因 (ob)发生遗传变异而不能产生正常的蛋白产物———Leptin ,而Leptin的最主要功能是反映脂肪组织含量 ,调节体重 ,使体重维持相对稳定 ,因此突变个体表现为肥胖。本文分析了不同品种猪内ob基因HinfI的多态性分布 ,该多态性是有点突变造成的。结果表明 ,中国地方猪种菜芜猪群体内C基因占优势 ,而长白猪和大约克群体中TT纯合子为 10 0 %。这种多态性分布与莱芜猪属肥胖型品种 ,而长白、约克夏猪属瘦肉型品种相吻合。更多还原

【Abstract】 Mutation of obese(ob)gene leads to the failure of producing leptin,while leptin is an important signal reflecting body fat mass and controlling body weight as a result the mutator shows fat.This paper reported the polymorphism analysis of Hinf I,which was caused by dot mutation,on ob gene in swine.The results indicated that C gene was domain in Laiwu swine,but wasn′t found in Yorkshire and Landrace pigs.This distribution of the polymorphism is consistent with the phenomenon that Laiwu pigs are fat while Yorkshire and Landrace pigs are thin.更多还原