【摘要】 目的　探讨动态检测急性胆管炎病人血清α GST对评估肝功能受损情况的临床意义。方法　 2 0 0 1～ 2 0 0 2年观察组为 32例急性胆管炎病人。对照组为 2 0位健康志愿者。α GST检测采用酶免疫测定法 (ELA)。谷丙转氨酶 (ALT)、谷草转氨酶 (AST)检测采用常规生化方法。结果　急性胆管炎病人血清中α GST在发病初期迅速升高 (P <0 0 5 ) ,并血清中所测α GST峰值变化于同期所测的ALT、AST值间比较明显提早 ,经治疗后α GST迅速下降 ,快于治疗后所测ALT、AST值的变化。结论　动态检测血清α GST浓度能更敏感的反映肝功能受损情况 ,对急性胆管炎病人的治疗有着重要的临床意义。更多还原

【Abstract】 Objective Investigate clinical value of serum α-glutathione s-fransferase(α-GST) as a marker of liver function damage in acute cholangitis.Methods The experimental group includes 32 patients of acute cholangitis and the control group 20 healthy volunteers.α-GST was detected by Enzyme immunoassay(EIA),ALT and AST was detected by routine methods.Results Serum α-GST goes up in experimental group contrast to control group (P<0.05).α-GST goes up faster and earlier than ATL and AST while it drops faster than ALT and AST after effective treatment in acute cholangitis.Conclusion α-GST is a more sensitive marker of liver function demage and could indicate the treatment of acute cholangitis.更多还原