【摘要】 目的　探讨妊高征患者血钙、尿素氮 (BUN)、肌酐 (Cr)水平及血BUN/Cr比值之间的相关性。方法　采用生化分析方法检测 3 11例妊高征患者的血钙、BUN、Cr及BUN/Cr比值 ,与 15 0例正常妊娠妇女及 72例非妊娠妇女对照。结果　妊高征患者血钙水平明显下降 ,与正常妊娠组、对照组比较 ,差异显著 (P <0 0 1) ,且下降程度与病情的严重程度呈正相关 ,均有显著差异 (P <0 0 1) ;血BUN、Cr水平上升 ,两者比较差异显著 (P <0 0 1) ,其升高程度反映妊高征病情的严重程度 (P <0 0 1)。结论　低血钙是妊高征的病因之一 ,血BUN、Cr水平及血BUN/Cr比值变化反映妊高征患者肾功能损害程度更多还原

【Abstract】 Objective To investigate the relativity of the level of serum calcium,blood urea nitrogen (BUN),and serum creatinine (SCr) and the ratio of BUN to SCr in patients with pregnancy induced hypertension (PIH).Methods Biochemistry was used to evaluate the level of serum calcium,BUN and SCr and the ratio of BUN to SCr in 311 PIH patients (study group),compared with 150 normal pregnant women and 72 non-pregnant women (control group).Results The serum level of calcium went on decreasing significantly in study group.There was positive correlation between the decrease of serum calcium level and the severity of the disease (P<0 01).The level of BUN and SCr in study group was significantly higher than that in control group,and the increase reflected the severity of the disease (P<0 01). Conclusion Hypocalcemia is a reason of PIH change of the level of BUN and SCr and the ratio of BUN to SCr can reflect the degree of renal function damage in patients with PIH.更多还原