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散血明目片对兔玻璃体积血肿瘤坏死因子-α表达的影响
An effects of sanxuemingmu(散血明目)tablet on the expression of tumor necrosis factor-αin vitreous hemorrhage of rabbits
【摘要】 目的 研究散血明目片对兔玻璃体积血肿瘤坏死因子 -α (TNF -α)表达的影响。方法 采用酶联免疫双抗体夹心法 (ELISA)检测积血玻璃体中TNF -α含量。结果 玻璃体积血 4周 ,散血明目片治疗组维持了TNF -α的高表达 ;8周TNF -α明显降到低水平。结论 散血明目片可以加速玻璃体积血的清除 ,抑制玻璃体内细胞增生的启动
【Abstract】 OBJECTIVE To observe effects of sanxuemingmu(散血明目) fablet on the expression of tumor necrosis factor-α(TNF-α) in vitreous hemorrhage o f rabbits.METHODS TNF-αlevels in eyes of rabbits with vitreous hemorrhage were measured by sandwich enzyme immunoassay technique(ELISA). RESULTS At four weeks, there was a higher expression of TNF-αlevels in the eyes of rabbits with vitreous hemorrhage. Eight weeks later, the TNF-α levels decreased evidently in the sanxuemingmu tablet group.CONCLUSIONS Sanxuemingmu tablet could accelerate absorption of vitreous hemorrhage and inhibit the start of proliferative vitreoretinopathy(PVR).
【Key words】 proliferative vitreoretinopathy; sanxuemjingmu; tumor necrosis factor-α(TNF-α);
- 【文献出处】 中国中医眼科杂志 ,Journal of Traditional Chinese Ophthalmology , 编辑部邮箱 ,2003年01期
- 【分类号】R276.7
- 【被引频次】4
- 【下载频次】66