【摘要】 本文探讨定量分析单味及多味复方中草药的药理活性的方法,为临床应用提供理论依据。利用两倍稀释法测定16种中草药对4种禽大肠杆菌体外抑菌的MIC;并选取24种两味组合,12种3～5味组合进行试验。结果单味中药对禽大肠杆菌的体外抑菌的MIC在3.9g/L至375g/L之间;24种两味中药组合的MIC在11.7g/L至250g/L之间,少数组合对各血清型大肠杆菌有拮抗作用;12种3～5味中药组合的MIC在11.7g/L至46.8g/L之间,全部组合表现协同作用,显示中药配伍优势。更多还原

【Abstract】 This paper studied the quantitative analysis method for single ingredient and several ingredients of Chinese herbal medicine pharmacological activities,and provided the theoretic basis for their clinical application.By means of2-fold diluent method,the MIC of antibacterial activities were obtained from16species of Chinese herbal Medicine,24species combinations of each2ingredient and12species of3～5ingredients.Four strains poultry E.coil were determined.The result indicated that the MIC of antibacterial activities from single ingredient ,2ingredient and3～5ingredients was from3.9g /L to375g /L,11.7g /L to250g /L and11.7g /L to46.8g /L respectively.It demonstrated that these combination of Chinese herbal medicine have enhanced cooperative advantage in pharmacological activities.更多还原