【摘要】 目的　探讨对二氯苯 (Paradichlorobenzen ,p -DCB)对变态反应性结膜炎的影响。 方法　采用杉木花粉抗血清免疫豚鼠复制实验性变态反应性结膜炎模型 ,并定量检测结膜炎轻重 ,观察不同浓度对二氯苯对其病情变化的影响。结果　空气中对二氯苯浓度仅为 4 1μg/m3时就对变态反应性结膜炎有增强作用。 41μg/m3时增强作用最明显。其增强作用持续 1周以上。结论　对二氯苯具有一定免疫毒性 ,低浓度时能明显加重变态反应性结膜炎。环境中微量化学物质污染可能是变态反应性疾病增多的重要因素更多还原

【Abstract】 Objective To study the effect of paradichlorobenzene on the allergic conjunctivitis.Methods The effects of different concentrations of paradichlorobenzene were observed by quantitatively measuring the conjunctivitis,which was based on the model of anti-cedar-pollen serum induced allergic conjunctivitis in guinea pigs.Results The allergic conjunctivitis was apparently aggravated when the concentration of paradichlorobenzene was over 4.1 μg/m 3 in the air,and most intensive aggravating effect was obtained at a dosage of 41 μg/m 3 paradichlorobenzene,which persisted for more than 1 week.Conclusion The paradichlorobenzene had the effect of immunotoxicity,and apparently aggravated allergic conjunctivitis at lower concentration.更多还原