【摘要】 目的 :观察三维适形放射治疗恶性梗阻性黄疸的疗效 ,探讨其更有效的治疗方法。方法 :1998年 10月～ 2 0 0 0年 12月 ,对 35例恶性梗阻性黄疸患者行三维适形放疗 ,每次 3～ 4Gy ,每周 5次 ,总共 10～ 12次。结果 :所有病例均完成治疗 ,病灶完全缓解率 (CR) 8例 ,占 2 4 % ,部份缓解 (PR) 2 2例 ,占 6 3% ,无变化 5例 ,占 13% ,总有效率 87%。 2 9例黄疸均有不同程度消退 ,没有严重的并发症发生。一、二年生存率分别为 70 %、2 1%。结论 :三维适形放疗对恶性梗阻性黄疸有较好的疗效 ,绝大多数患者均能耐受 ,是治疗恶性梗阻性黄疸的一种有效方法。更多还原

【Abstract】 Purpose:To evaluate the effect of 3DRT for malignant biliary obstruction and to find a more effective method of treatment.Methods:Form October 1998 to September 2000,35 patients with malignant biliary obstruction ,3-4 Gy of 5 fractions a week to total doses from 38 to 48 Gy.Results:All cases completed radiation. CR rates were 24%,PR rates were 63%,the overal response rate (CR+PR) was 87%. A significant decrease of bilirubin levels was observed in 29 patients,no serious complications occured. 1-2 year survival rates were 70% and 21%.Conclusions:3DRT is well tolerated in most patients with malignant biliary obstruction,its effect is better than the conventional radiation and it is a more effective treatment for the malignant biliary obstruction.更多还原