【摘要】 目的 :分析普查自然人群 41 3 1 64人EB病毒壳抗原的免疫球蛋白A抗体 (VCA IgA)和早期抗原抗体 (EA IgA)阳性与性别、年龄及鼻咽癌检出关系。 方法 :应用免疫酶法检测VCA IgA和EA IgA抗体 ,间接鼻咽镜检查 ,病理组织学诊断。结果 :普查自然人群 41 3 1 64人检出VCA IgA抗体阳性 1 2 62 9人 ,阳性率 3 .0 6 % ,抗体阳性率高低与性别无关 ,与年龄高低呈正相关趋势。检出鼻咽癌 1 74例 ,早期 1 51例 ,早诊率 86 .78% ,普查自然人群鼻咽癌检出率 42 .1 1 /1 0万。鼻咽癌检出率高低与年龄呈正相关趋势。结论 :本法普查鼻咽癌可达提高早诊率目的 ,若普查重点能放在 35岁以上人群意义更大更多还原

【Abstract】 Purpose:To analyze the correlation of positive VCA IgA and EA IgA antibodies, sex and age to diagnosis of NPC through a survey of 413 164 persons. Methods:To diagnose NPC by detecting VCA IgA and EA IgA antibodies with ELISA, indirect nasopharynxscopes and histopathologic examination. Results:In 413 164 persons, 12 629 cases with positive VCA IgA antibody were found. The positive rate was 3.06%. The results indicated that the rate of positive antibody was not related to sex, but was associated with age. In those cases, 174 were diagnosed as NPC, and 151 were in early stage of NPC. The early diagnosis rate was 86.78%, and over all NPC diagnosis rate was 42.11/100000 in the survey. The diagnosis rate was also related with age. Conclusions:Methods of survey can be beneficial for early prevention and early diagnosis of NPC, especially for those aged over 35 year.更多还原