节点文献
硒、维生素E、锌与低硒、富锰引起大鼠心肌损伤的关系
The relationship between given selenium, vitamin E zinc and cardiac injury by low selenium and rich manganese
【摘要】 目的 探讨硒、维生素E(VE)、锌单因素及复合因素对低硒、富锰心肌损伤的影响。方法 用低硒、富锰人工半合成饲料喂饲大白鼠 8周。补充硒 (0 .3mg/kg)或VE(2 5 0mg/kg)或锌 (2 0 0mg/kg)。 结果 单因素硒、VE、锌及复合因素均可使血清谷胱甘肽过氧化物酶 (GSH Px)活性提高 ,使心肌组织脂质过氧化物(LPO)值明显降低 ,心肌坏死检出率有降低的趋势。结论 复合因素好于单因素 ,3因素明显好于双因素
【Abstract】 Objective To study the effect of given selenium,vitamin E,zinc on the cardiac injury by low selenium and rich manganese.Methods Fed on basic diet with low selenium and rich manganses by adding selenium(0.3 mg/kg) vitamin E(250 mg/kg), zinc(200 mg/kg) in rats for eight weeks.Results The results showed that the activity of GSH Px in serum could be increased obviously and the content of LPO of rats myocardium could be decreased obviously and the ratio of myocardic necrosis could be reduced by giving selenium, vitamin E, zinc respectively or complexly.Conclusions The double factors are better than single factor,the three factor is better than the double ones.
- 【文献出处】 中国地方病学杂志 ,Chinese Journal of Endemiology , 编辑部邮箱 ,2003年02期
- 【分类号】R363
- 【被引频次】10
- 【下载频次】73