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福参的苷类成分

Glycosides from root of Angelica morii

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【作者】 孙视石赟蓉孔令义张涵庆贺善安

【Author】 SUN Shi 1,2 , SHI Yun rong 1, KONG Ling yi 1, ZHANG Han qing 2, HE Shan an 2 (1 Institute of Botany, Jiangsu Province & CAS, Nanjing 210014, China; 2 Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210038, China)

【机构】 江苏省·中国科学院植物研究所中国药科大学天然药物化学教研室中国药科大学天然药物化学教研室 江苏南京210014江苏南京210038江苏南京210014江苏南京210038

【摘要】 目的 从福参 Angelica morii提取分离活性成分。方法 采用乙醇提取 ,溶剂萃取 ,大孔树脂、聚酰胺、硅胶柱层析 ,LH-2 0、重结晶等纯化 ,对福参饮片进行系统提取分离 ;运用波谱学方法及理化常数对照进行结构鉴定。结果 从正丁醇和水部分分离到 6个苷类化合物 ,分别为升麻素苷 (prim-O-glucosylcimifugin, )、紫花前胡苷(marmesinin, )、芹菜素 7-O-β-D-葡萄糖苷 (apigenin 7-O-β-D-glucoside, )、木犀草素 7-O-β-D葡萄糖苷 (lute-olin 7-O-β-D-glucoside, ) ,umbeliferone 7-apiosylglucoside ( )和胡萝卜苷 (daucosterol, )。结论  6个化合物均为首次从该植物中分得 ;化合物 首次从当归属中分得

【Abstract】 Object To isolate the bioactive constituents from the root of Angelica morii Hayata Me thods The constituents were extracted with 95% alcohol, isolated via column macroporous resin, polyamide, silica gel, and purified by LH 20 and recrystallization The structures were elucidated by means of physico chemical data and UV, IR, 1HNMR , and 13 CNMR Results Six glycosides were isolated as prim O glucosylcimifugin (Ⅰ), marmesinin (Ⅱ), apigenin 7 O β D glucoside (Ⅲ), luteolin 7 O β D glucoside (Ⅳ), umbeliferone 7 apiosylglucoside (Ⅴ), and daucosterol (Ⅵ) Conclusion All the above compounds are found in the species and compound Ⅲ is found in the plants of Angelica L for the first time

【关键词】 福参苷类当归属
【Key words】 the root of Angelica morii HayataglycosidesAngelica L
  • 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,2003年08期
  • 【分类号】R284.1
  • 【被引频次】11
  • 【下载频次】253
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