【摘要】 目的　初步探讨单核细胞趋化因子 1(monocytechemoattractantprotein 1,MCP 1)在银屑病发病机制中的作用。方法　分离处于不同病期的寻常性银屑病患者外周血血清 ,通过酶联免疫吸附 (ELISA)法检测银屑病患者血清中MCP 1的水平 ;同时比较了不同病期中血清MCP 1水平。结果　银屑病患者血清中MCP 1水平明显高于健康对照组 ,但MCP 1的水平并不随病期的变化而变化。结论　银屑病外周血MCP 1的高表达可能与银屑病的发病有关。更多还原

【Abstract】 Objective To investigate the effects of MCP-1 in the pathogenesis of psoriasis.Methods The concentration of MCP-1 in the serum from psoriasis vulgaris was determined by ELISA and the levels of MCP-1 between the different stages of disease were compared.Results The concentration of MCP-1 in the serum from psoriatic peripheral blood was significantly increased.But the levels of MCP-1 did not change along with the development of disease.Conclusion High levels of MCP-1 in peripheral blood might be related to the pathogenesis of psoriasis.更多还原