节点文献
从邻苯二酚合成3,4-亚甲二氧基苯甲醇
Synthesis of Piperonol from Catechol
【Abstract】 A facile synthesis of piperonol is reported from catechol. Reacted catechol with excess dichloromethane in an autoclave under nitrogen atmosphere gave 88 4% 1,3-benzodioxole(1), which is directly chlo romethylated to yield 90 1% 5-chloromethyl 1,3-benzodioxole(2) by hydrogen chloride saturated triformol. 2 can easily convert to piperonal by treatment with alcoholic solution of Na 2CO 3 in yield of 97 7%. The total yield is 78%.
【基金】 国家自然科学基金 ( 6 0 0 710 0 1);江苏省高新技术 (BG2 0 0 10 10 )资助项目
- 【文献出处】 应用化学 ,Chinese Journal of Applied Chemistry , 编辑部邮箱 ,2003年03期
- 【分类号】O625.511
- 【被引频次】16
- 【下载频次】536