【摘要】 利用Pirkle型(S,S)-Whelk-O1手性固定相对2,2-二苯环丙烷羧酸农药中间体进行了对映体分离研究。考察了在流动相正己烷中,异丙醇的浓度变化对手性分离的影响,初步探讨了其手性识别机理,结果表明,(S,S)-Whelk-O1上溶质与固定相之间主要是通过吸引作用发生手性识别。更多还原

【Abstract】 Separation of the enantiomers of 2,2-biphenyl-cyclopropanecarboxylic acid which is a pesticide intermediate has been studied in (s, s)-Whelk-O1chiral column by HPLC. Effect of concentration of isopropanol in the mobile phase has been investigated and chiral separation mechanism has also been discussed.更多还原