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酸枣仁皂苷E的结构鉴定

Structure identification of jujuboside E

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【作者】 白焱晶程功陶晶王邠赵玉英刘毅马立斌涂光忠

【Author】 BAI Yan-jing 1, CHENG Gong 1, TAO Jing 1, WANG Bin 1, ZHAO Yu-ying 1* , LIU Yi 1, MA Li-bin 2, TU Guang-zhong 2 (1. Division of Natural Medical Chemistry, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China; 2. Beijing Institute of Microchemistry, Beijing 100091, China)

【机构】 北京大学药学院天然药物化学研究室北京市微量化学所北京市微量化学所 北京100083北京100083北京100091北京100091

【摘要】 目的 研究酸枣仁 (ZiziphusjujubaMillvar.spinosa)的化学成分。方法 用各种色谱方法分离酸枣仁的化学成分 ,用波谱 (IR ,UV ,MS ,NMR)方法鉴定结构。结果 从酸枣的干燥种子中分离得到 7个化合物 ,分别鉴定为酸枣仁皂苷E(1,jujubosideE) ,酸枣仁皂苷B(2 ,jujubosideB)及酸枣仁皂苷A(3,jujubosideA) ,白桦酯酸 (4,betulicacid) ,硬脂酸 (5 ,stearicacid) ,蔗糖 (6 ,sucrose)和肌苷 (7,inosine)。结论 化合物 1为新化合物 ,5 ,6和 7为首次从酸枣仁中获得。

【Abstract】 Aim To study the chemical constituents of the seeds of Ziziphus jujuba Mill var. spinosa (Bunge) Hu ex. H.F. Chou. Methods To separate the constituents by using various kinds of chromatography methods and identify their structures on the basis of spectral analysis. Results Seven compounds were isolated. Their structures were established as jujuboside E (1), jujuboside B (2), jujuboside A (3), betulic acid (4), stearic acid (5), sucrose (6) and inosine (7). Conclusion Compound 1 is a new compound named jujuboside E. Compounds 5, 6, 7 were isolated for the first time from this plant.

  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,2003年12期
  • 【分类号】R284
  • 【被引频次】72
  • 【下载频次】708
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