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广藿香的两个化学型及产地与采收期对其挥发油成分的影响

Two chemotypes of Pogostemon cablin and influence of region of cultivation and harvesting time on volatile oil composition

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【作者】 罗集鹏刘玉萍冯毅凡郭晓玲曹晖

【Author】 LUO Ji peng 1, LIU Yu ping 2, FENG Yi fan 1, GUO Xiao ling 1, CAO Hui 3* (1. Guangdong College of Pharmacy, Guangzhou 510224, China; 2. Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China; 3. National Engineering Research Center for Modernization of Traditional Chinese Medicine, Zhuhai 519020, China)

【机构】 广东药学院中国中医研究院中药研究所国家中药现代化工程技术研究中心 广东广州510224北京100700广东广州510224广东珠海519020

【摘要】 目的 比较不同产地、不同采收期的广藿香挥发油主要成分的含量 ,为广藿香物种和道地性与品质评价提供可靠依据。方法 GC MS联用技术。结果 吴川、遂溪、雷州和万宁产广藿香含油率较广州和高要产高 4~ 6倍。牌香类的挥发油中均含有较多量的广藿香酮 ;琼香类的挥发油中不含或含较少量的广藿香酮 ,但含较多量的广藿香醇。不同采收期的广藿香挥发油从 7月至 11月呈增加趋势。结论 根据挥发油成分的不同 ,将不同产地的广藿香分为 2个化学型 ,即广藿香酮型 (牌香类 )和广藿香醇型 (琼香类 ) ,此与基因分析结果 (matK和 18SrRNA序列 )相一致

【Abstract】 Aim To analyze and compare the constituents of the volatile oil of Pogostemon cablin collected from different regions of cultivation and harvesting times in order to evaluate the quality of Shipai Huoxiang and to expound the chemical intension of Pogostemon cablin . Methods The combination of GC and MS. Results The volatile oil compositions of Herba Pogostemonis collected from various of cultivation regions and harvesting times are obviously different. Based on the chemical differences of the volatile oil compositions, Pogostemon cablin is divided into two chemotypes, Pogostone type and Patchouliol type. The former was cultivated in Guangzhou and Gaoyao regions, locally named as “Shipai Huoxiang”; the latter was locally named as “Hainan Huoxiang”, cultivated in Wuchuan, Suixi and Leizhou regions of Guangdong Province and Wanning region of Hainan Province. The Pogostone type contains rich oxygenated components, especially pogostone in the volatile oil compositions and poor non oxygenated composition with patchouliol. The above chemical data may be used as evaluation standard for the authentic Shipai Huoxiang. The Patchouliol type contains similar quantities of oxygenated and non oxygenated composition, especially rich patchouliol with poor pogostone in oxygenated compositions, rich δ guaiene and α guaiene in non oxygenation compositions. The contents of volatile oil and their constituents were varied due to different harvesting time. The yields of pogostone and volatile oil of Shipai Huoxiang was higher in July. The quality of the samples collected in this month was better. Conclusion According to the volatile oil compositions, there are two chemotypes (Pogostone type and Patchouliol type) in Pogostemon cablin plant. These two chemotypes correspond to thegenotypes of plastid mat K gene and nuclear 18S rRNA gene by cluster analysis.

【基金】 广东省自然科学基金;广东省中医药管理局资助课题
  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,2003年04期
  • 【分类号】R284
  • 【被引频次】123
  • 【下载频次】1093
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