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透明质酸钠预防手屈指肌腱粘连回顾性对照研究

Retrospective Controlled Study on Sodium Hyaluronate in prevent of Adhesion of Flexor Tendon in Hand Surgery

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【作者】 张殿玺白建兰杨文玉

【Author】 Zhang Dianxi 1,Bai Jianlan 1,Yang Wenyu 2 1the Xinzhou People’s Hospital of Shanxi, Xinzhou 034000 2The People’s Hospital in Wenshui of Shanxi

【机构】 忻州市医院山西省文水县医院 山西忻州034000山西忻州034000

【摘要】 目的 :评价透明质酸钠防治手屈指肌腱粘连的有效性和安全性。方法 :回顾性分析 5 6例手屈指肌腱手术者 ,在肌腱损伤修复部鞘内或局部 ,分别注入透明质酸钠凝胶制剂。A组 3 0例 ,注入 2 0mg/ 2mL ;B组 2 8例不用透明质酸钠。其它治疗两组相同 ;术后 4,8,12周测定相关部位的功能、疼痛、肿胀情况 ,按关节功能、握拳功能评价透明质酸钠预防粘连的效果。结果 :5 6例经 4~ 12周随访 ,A组优良率 70 .0 0 % ,无明显不良反应。B组 3 9.2 9% ,两组比较P <0 .0 5。结论 :透明质酸钠凝胶预防术后屈指肌腱粘连有明显的作用 ,作用安全、方便

【Abstract】 Objective: To evaluate the effects and safety of sodium hyaluronate on adhesion prevention of flexor tendon after the hand surgery. Method: In 56 cases of patients recieving the flexor tendon surgery, sodium hyaluronate jelly prepartions were injected into the tendon sheath before suture and a retrospective analysis was conducted. The preparation(20 mg/2 mL) was given for group A (30 patients), the controlled group (group B, 28 patients) were treated in the same way except injection of sodium hyaluronate. The functions of afflicted fingers including flexibility, pain and swelling were measured immediately and at the fourth, eighth, and twelfth weeks after operation. Result: All 56 patients were followed up 4 to 12 weeks. The effective rate in the group A was 70.0%, and no negative effects were found, that in the controlled group was 39.29%, There were significant difference between both groups(P< 0.05).Conclusion: Sodium hyaluronate preparations have effects in adhesion prevention after flexor tendon surgery with safety and expedience.

【关键词】 透明质酸钠屈指肌腱预防粘连
【Key words】 Sodium hyaluronateFlexor tendonPreventiononAdhesion
  • 【文献出处】 药物流行病学杂志 ,Chinese Journal of Pharmaco Epidemiology , 编辑部邮箱 ,2003年01期
  • 【分类号】R686
  • 【被引频次】17
  • 【下载频次】52
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