节点文献
抗前列腺特异性抗原单克隆抗体的制备、鉴定及初步应用
Preparation, characterization and application of monoclonal antibodies for prostate-specific antigen
【摘要】 通过杂交瘤技术制备抗前列腺特异性抗原(PSA)单抗细胞株,共获得68株稳定分泌PSA单克隆抗体的细胞株,并对其中与总PSA(t-PSA)反应的12株进行了详细的免疫特性鉴定.
【Abstract】 68 mouse hybridoma cell lines which stably secreted monoclonal antibodies against human prostate-specific antigen (PSA) were obtained through hybridoma technique. 12 among these McAbs which reacted with total PSA (tPSA) were identified for their immunological characters in detail.
【关键词】 前列腺特异性抗原;
亲和常数;
单克隆抗体;
抗原表位;
【Key words】 prostate-specific antigen (PSA); affinity constant; monoclonal antibody; epitope;
【Key words】 prostate-specific antigen (PSA); affinity constant; monoclonal antibody; epitope;
【基金】 云南省科委省院省校科技合作项目(99YB02).
- 【文献出处】 云南大学学报(自然科学版) ,Journal of Yunnan University (Natural Sciences) , 编辑部邮箱 ,2003年S1期
- 【分类号】Q813.2
- 【被引频次】5
- 【下载频次】101