【摘要】 目的 :探讨纳洛酮治疗急性脑梗死的临床疗效。方法 :将 12 2例急性脑梗死病人随机分为纳洛酮组 (6 2例 )和对照组 (6 0例 )。纳洛酮组用 5 %GS2 5 0ml+纳络酮注射液 0 .8mg静滴 ,每日 2次 ;对照组用 5 %GS 2 5 0ml +复方丹参 16ml静滴 ,每日 1次。疗程均为 14d ,在 1个疗程后进行疗效和起效时间比较。结果 :纳洛酮组总有效率为 93.5 % ,对照组为 76 .7% ,两组比较有显著性差异 (P <0 .0 5 ) ;纳洛酮组的起效时间明显快于对照组 (P <0 .0 5 )。结论 :纳洛酮治疗急性脑梗死临床疗效显著。更多还原

【Abstract】 AIM: To investigate the clinical efficacy of naloxone in tre at ment of patients with acute cerebral infarction (ACI). METHODS: 122 patients were randomly assigned to treatment group (n=62) an d control group (n=60). The 5% GS 250 ml+naloxone injection 0. 8 mg were infused intravenously twice a day in treatment group and the 5% GS 2 50 ml+danshen injection 16 ml once a day by the same way in control group. The t reatments lasted for 14 days. The curative effects before and after 14-days th erapy and effect times in two groups were observed. RESULTS: The total effective rate in treatment group ( 93.5 %) was significantly higher th an those ( 76.7 %) in control group (P< 0.05 ). The effect t imes in treatment group were significantly superior to those in control group ( P< 0.05 ). CONCLUSION: Naloxone shows a better clinical efficacy in treatment of patients with ACI.更多还原