【摘要】 在人体生物医学研究中 ,对照组的受试者应得到公认有效的干预。然而 ,在有些特定的情况下 ,使用安慰剂、不治疗或其他替代的方法作对照在伦理上是可接受的。本文从伦理学角度对这些特定的情况做了详细的阐述 ,并提出了安慰剂对照试验中最小化风险的方法更多还原

【Abstract】 As a general rule, research subjects in the control group of a biomedical research involving human subjects should receive an established effective intervention. In some circumstances, however, it may be ethically acceptable to use an alternative comparator, such as placebo, “no treatment” or other effective alternative. This article discusses these special circumstances in detail, and puts forward means of minimizing harm to placebo control subjects.更多还原