Autologous human IPE cells can be easily obtained by iridectomy without harmful effect to the patient. They can transdifferentiate into RPE cells. It has been shown that in vitro IPE cells can acquire the ability to phagocytose rod outer segments (ROS).So IPE cells seem to be ideal substitute for RPE cells to be transplanted into the subretinal space of patients with degenerative diseases. Effect of IPE and RPE cells was compared and the culture methods of IPE cells and its transplantation were reviewed in ...
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