In the investigation of novel baicalein derivatives with bioactivity, a series of Mannich base derivatives of baicalein were designed and synthesized at C-8 in A-ring through Mannich reaction. The characteristic of this reaction was mild condition, easier purification and good yield (>80%). Furthermore, two new six-ring dihydrobenzoxazine compounds 5h and 5i were obtained when the ratio of primary amine and HCHO was 1∶2. Mannich base hydrochloride compounds 4b and 4j were prepared in hydrochloric acid for t...
| 
推荐 
点击下列相关研究机构和相关文献作者，可以直接查到这些机构和作者被《中国知识资源总库》收录的其它文献，使您全面了解该机构和该作者的研究动态和历史。
