【摘要】 目的 :探讨非穿透性小梁手术 (NPTS)联合羊膜移植治疗开角型青光眼的机制及疗效评价。寻找透明质酸钠凝胶植入材料替代物。方法 :对 18例 2 5只开角型青光眼患者行非穿透性小梁手术联合羊膜移植 ,术后观察视力、眼压、滤过泡及眼内反应 ,随访时间最短 30天 ,最长 4 2 0天。结果 :术前 2 5只眼平均眼压为 (38 2± 14 4 )mmHg ,2 5只眼术后 3只眼眼压高于 2 1mmHg ,经降眼压药物治疗后 2只眼仍高达 2 8mmHg以上 ,余眼压均控制在 7～ 2 0mmHg之内 ,术后 2个月手术成功率为 88% ,条件成功率为 92 % ,术后 3个月手术成功率为 82 % ,条件成功率为 88%。术后视力均有显著提高 ,滤过泡扁平弥漫 ,轻微充血。术中、术后未出现浅前房、前房出血、玻璃体脱出、脉络膜脱离等并发症。结论 :非穿透性小梁手术联合羊膜移植能安全、有效地降低眼压 ,为非穿透性小梁手术提供了有效安全植入材料。可广泛用于开角型青光眼的治疗更多还原

【Abstract】 Objective:To evaluate the values of amniotic membrane implantation in the non penetrating trabeculectomy for open angle glaucoma.Methods:Non penetrating trabeculectomy combined with amniotic membrane implantation were operated on 18 cases(25 eyes) of open angle glaucoma.The visual acuity,intraocular pressure(IOP),filtration bleb and ocular reaction were recorded after operation.The patients were followed up for 30～240 days.Results:The average IOP of 25 eyes was 38 2±14 4 mmHg before operation. After operation,IOP of 3 eyes was higher than 21 mmHg and that of the 2 eyes was still 28 mmHg after medical treatment while IOP of the other 20 eyes was within 7～20 mmHg.Two months after operation,the successful rate of operation was 88%and the successful rate of condition was 92%,and that at three months after operation was 82% and 88% respectively.There were no shallowing of anterior chamber,hyphema,prolapse of vitreous or detachment of choroid during and after operation.Conclusion:Using amniotic membrane implant in non penetrating trabeculectomy can lower the IOP safely and effectively.Amniotic membrane is a safe and effective material for antiglaucoma surgery in open angle glaucoma.更多还原