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油漆工淋巴细胞染色体畸变率和微核率的变化

The rate of chromosome aberration and lymphocyte micronucleus in painter

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【作者】 崔金山吴咏今王素凡金云生

【Author】 CUI Jin-shan, WU Yong-jin, WANG Su-fan, et al (Department of Preventive Medicine, Shenyang Medical College, Shenyang 110030, China)

【机构】 沈阳医学院毒理学教研室本溪市职业病防治院本溪市疾病预防控制中心本溪市职业病防治院 辽宁沈阳110034117032117032

【摘要】 目的 探讨居室装饰油漆工外周血淋巴细胞染色体畸变率和微核发生率的变化。方法 应用气相色谱法测定工作场所苯等有机溶剂浓度 ,按常规方法检测外周血淋巴细胞染色体畸变率和微核发生率。结果 在工作场所空气中苯等有机溶剂浓度超标 2~ 2 5倍 ,接触组工人外周血淋巴细胞微核发生率为 7 12‰ ,对照组为 1 5 6‰ ;染色体畸变率接触组为 2 62 % ,对照组为 0 62 % ,接触组均显著高于对照组 (P <0 0 1)。结论 油漆工作业场所苯等有机溶剂浓度严重超标 ,致使作业工人外周血淋巴细胞染色体畸变率和微核发生率升高。

【Abstract】 Objective To study the possibility and degree of chromosome aberration and micronucleus rates of painting in indoor decoration. Methods 30 workers who had been working in indoor painting for long time were randomly selected from building labour market, half for men and half for women. Concentrations of benzene etc. in workplaces were measured. Chromosome aberration and micronucleus rates of lymphocyte in periphery blood were tested by regular method. Results Concentrations of benzene etc. in workplaces air were 2~25 times over hygienic standard. Micronucleus rates of lymphocyte in periphery blood were 7.12‰ in exposure groups and 1.56‰ in control; chromosome aberration rate were 2.62% in exposure groups and 0.62% in control. The two indices in exposure group were higher than those in control ( P <0.01). Conclusion Concentrations of benzene etc. in workplaces air seriously exceeded hygienic standard in indoor decoration. The increase of chromosome aberration and micronucleus rates of lymphocyte in periphery blood were observed.

  • 【文献出处】 中国职业医学 ,Chinese Occupational Medicine , 编辑部邮箱 ,2003年03期
  • 【分类号】R135
  • 【被引频次】8
  • 【下载频次】78
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