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白芍总苷的药理作用及其在自身免疫性疾病中的应用
Pharmaceutical effects of total glucosides of peony and its application in autoimmune disease
【摘要】 研究发现白芍总苷具有多途径抑制自身免疫反应 ,以及抗炎、止痛、保肝的作用 ,对类风湿性关节炎 (RA)、系统性红斑狼疮 (SLE)等自身免疫病有确切疗效。本文对白芍总苷在细胞、体液免疫 ,抗炎等方面的基础研究 ,以及在自身免疫病治疗的临床研究予以综述
【Abstract】 It was found that total glucosides of paeony (TGP) had inhibitive effects on autoimmune response via variant pathway. It also had effects of inflammation suppressing, analgesia, and hepatic protecting. It had precisely therapeutic effect on autoimmune diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). This presenting review has summarized the studies of TGP on cellular, humoral immunity, anti inflammation, and clinical studies on auto immune diseases.
【关键词】 自身免疫疾病;
药物治疗;
关节炎,类风湿;
红斑狼疮,系统性;
白芍总苷;
芍药;
葡糖苷类;
【Key words】 autoimmune diseases; drug therapy; arthritis, rheumatoid; lupus erythematosus, systemic; total glucosides of paeonia; paeonia lactiflora; glucosides;
【Key words】 autoimmune diseases; drug therapy; arthritis, rheumatoid; lupus erythematosus, systemic; total glucosides of paeonia; paeonia lactiflora; glucosides;
- 【文献出处】 中国新药与临床杂志 ,Chinese Journal of New Drugs and Clinical Remedies , 编辑部邮箱 ,2003年11期
- 【分类号】R285
- 【被引频次】491
- 【下载频次】3906