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消化性溃疡的病因和药物治疗

Etiologic factor and treatment of peptic ulcer disease

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【作者】 沈玉根刘建成陈士葆

【Author】 SHEN Yu-gen 1, LIU Jian-cheng 1, CHEN Shi-bao 2 (1. Qinpu District, Jinze Public Health Centre, SHANGHAI 201718, China; 2. Depatment of Gastroenterology, Changzheng Hospital, The Second military Unive rsity of PLA, SHANGHAI 200003, China)

【机构】 青浦区金泽镇卫生院中国人民解放军第二军医大学长征医院消化内科 上海201718上海201718上海200003

【摘要】 消化性溃疡是我国人群中常见病之一 ,各种因素如幽门螺杆菌感染、药物、遗传及社会心理因素等均可诱发或促进本病的发生。组胺H2 受体拮抗剂如法莫替丁、尼扎替丁等和质子泵抑制剂如奥美拉唑、兰索拉唑等抗酸分泌药物与胃粘膜保护剂如硫糖铝混悬液、胶态次枸椽酸铋等联合应用可有效的治疗消化性溃疡病。应用奥美拉唑、阿莫西林及克拉霉素三联 7d治疗可有效的根治幽门螺杆菌和促进溃疡愈合

【Abstract】 The peptic ulcer (PU) disease is one of the common diseases in our country popul ation. Multiple factors, such as Helicobacter pylori (Hp) infection, drugs, heridity and society-psychologic factor can induce and / or promote the occurr ence of PU disease. H 2-receptor antagonist drugs (famotidine, nizatidine) and proton pump inhibitors (PPI) (omeprazole, lansoprazole) conbined with gastric m ucosa protective drugs (sucralfate, bismuth subcitrate) are effective in treatin g peptic ulcer. One triple therapy with omeprazole, amoxycillin and clarithromyc in for 7 d is highly effective in eradicating Hp and healing peptic ulcers.

  • 【文献出处】 中国新药与临床杂志 ,Chinese Journal of New Drugs and Clinical Remedies , 编辑部邮箱 ,2003年10期
  • 【分类号】R573.1
  • 【被引频次】60
  • 【下载频次】1062
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