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高甘油三酯血症对动脉弹性功能的影响

Effect of Hypertriglyceridemia on arterial elasticity

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【作者】 陶军周舸王礼春高修仁廖新学陈国伟曾群英马虹

【Author】 Tao Jun,Zhou Ke,Wang Lichun,et al.Department of Cardiology,The First Affiliated Hospital,Sun-Yat sen University,Guangzhou 510080,China

【机构】 广州中山大学附属第一医院心内科广州中山大学附属第一医院心内科 510080510080

【摘要】 目的 研究高甘油三酯血症患者动脉弹性功能的变化。方法 采用动脉弹性功能测定仪CVProfilorDo -2 0 2 0检测 12例高甘油三酯血症患者和 15例健康志愿者大动脉弹性指数C1和小动脉弹性指数C2。结果 高甘油三酯血症患者和对照组的大动脉弹性指数C1无明显差别 (13 4± 3 6vs 14 3± 3 9ml/mmHg× 10 ) ,与对照组比较 ,高甘油三酯血症患者小动脉弹性指数C2明显降低 (6 3± 1 9vs 8 5± 2 4ml/mmHg× 10 0 ,P <0 0 5 )。结论 高甘油三酯血症损伤小动脉弹性指数C2 ,提示血管内皮细胞功能障碍可能是高甘油三酯血症导致冠心病发病和死率增加的原因之一

【Abstract】 Objective To study the effect of hypertriglyceridemia on arterial elasticity.Methods Large artery and small artery elasticity indices (c1 and C2) were measured in 12 subjects with hypertriglyceridemia and 15 healthy volunteers by using CVProfilorDO-2020 instrument.Results There was no difference in large artery elasticity index c1 between the two groups (13 4±3 6 vs 14 3±3 9ml/mmHg×10).However,the small artery elasticity index C2 was lower in subjects with hyperiglyceridemia than that in healthy volunteers (6 3±1 9 vs 8 5±2 4ml/mmHg×100,P<0 05).Conclusions Small artery elasticity index C2 is impaired in hypertriglyceridemic patients,indicanting that endothelial dysfunction could be responsible for the increased morbidity and mortality of coronary heart disease in hypertriglyceridemic patients.

  • 【文献出处】 心脑血管病防治 ,Prevention and Treatment of Cardio-Cerebral Vascular Disease , 编辑部邮箱 ,2003年04期
  • 【分类号】R589.2
  • 【被引频次】17
  • 【下载频次】139
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