【摘要】 目的　观察“防蚴灵”涂肤剂预防血吸虫尾蚴感染的效果。方法　用氯硝柳胺加透皮促进剂制成 1% - 2 %浓度的“防蚴灵”,对感染前 1、2、3、4、5、6、7d涂肤的小白鼠和家兔分别进行预防血吸虫尾蚴感染的试验 ,并与对照组比较。结果　小鼠在感染前 1- 4 d,涂 1%防蚴灵 1次 ,其减虫率为 10 0 % ,在感染前 5 - 7d涂药 1次 ,减虫率为 99.7% - 88.1%。家兔感染前 3- 7d涂 2 %的防蚴灵1次 ,减虫率为 86 .4 % - 80 .1%。结论　涂肤剂“防蚴灵”具有较长时间的防御血吸虫尾蚴侵肤感染的功效更多还原

【Abstract】 ObjectiveTo observe the effe ct of varnish“Fangyouling” preventing skin invasion from Schist osoma cercariae. MethodsThe“Fangyouling” was made from niclo s amide and permeable improver, and the concentration of the drug was 1%-2%. Exper imenta l mice and rabbits were spread with “Fangyouling” on the abdomen skin without h air at day 1,2,3,4,5,6,7 respectively before infection, compaired with cont rol group. ResultsThe worm reduction rates of mice which were spread with drug 1-4 days and 5-7 days before infection were 100 % and 99 7%-88 1%. The worm reduction rates of rabbits which were spread with dr ug 3-7 days before infection were 86 4%-80 1%. ConclusionThe“Fangyouling” has long efficiency on preventing Schistosoma cercariae from invading skin.更多还原