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妊娠期妇女凝血指标变化的临床意义

Study on the Variation of Coagulation Indexes in Pregnancy

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【作者】 林向华梁穆兴段朝晖黄松音范侠

【Author】 UN Xiang-hua , LIANG Mux-ing, DUAN Zhao-hui, HUANG Song-yin FAN XiaDepartment of Laboratory, the Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou ,510120

【机构】 中山大学附属第二医院检验科中山大学附属第二医院检验科 广州510120广州510120

【摘要】 目的:探讨妊娠期妇女凝血指标变化的临床意义。方法:用法国STAGO compact全自动凝血分析仪对39例正常对照、76例中孕组(孕20~28周)及54例晚孕组(孕37~40周)妇女的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、纤维蛋白原(Fbg)、凝血酶时间(TT)进行检测。结果:中孕组、晚孕组与正常对照组相比,APTT及TT缩短,Fbg水平升高,差别均有非常显著性意义(P<0.01),PT无统计学差异(P<0.05);晚孕期与中孕期相比,PT和APTT有所延长,存在显著性差异(P<0.05)。结论:妊娠期妇女凝血功能有增强的趋势,机体呈现高凝状态,可能有利于产后快速有效止血。

【Abstract】 Objective: To investigate the level and clinical significance of coagulation indexes in pregnancy. Methods: Prothrombin time(PT) , activated partial thromboplastin time(APTT), fibrinogen(Fbg) and thrombin time (IT) were determined in both normal group, pregnancies at middle stage and late stage, and analyze the correlation between them. Results: APTT and TT were shorten while Fbg increases obviously(P < 0.01), there was no significant difference between pregnancy and normal group in PT(P>0.05) . PT and APTT of the late pregnancies were a little longer than the middle stage(P<0.05) . Conclusion: There is a hypercoagulability state in pregnancy.

  • 【文献出处】 血栓与止血学 ,Chinese Journal of Thrombosis and Hemostasis , 编辑部邮箱 ,2003年01期
  • 【分类号】R714.1
  • 【被引频次】8
  • 【下载频次】104
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