Objective To explore the role of astrocyte in chronic restraint stress.Methods Rats were divided into stress and control groups. The stress rats were restrained for 6 hours every day for 21 days,and then the behavior of rats in two groups was tested respectively by Y-maze.The expression of GFAP in the rats' hippocampus of both groups was investigated with immunohistochemical method.Results The experiment rat's ability of spatial learning and memory declined(P<0.05).And the immunoreactivities of the GFAP wer...