【摘要】 目的:探讨压力控制通气 (PCV )和容量控制通气 (VCV )对呼吸力学和氧合作用的影响。 方法:对 2 0例急性呼吸窘迫综合征 (ARDS)患者进行机械通气 (MV )治疗。A组先用 PCV,分别保持潮气量 (VT)和平均气道压(MPaw)不变 ,后改为 VCV;B组先用 VCV ,后改为 PCV,保持血氧饱和度平稳 0 .5 h后监测指标。受试者在 5 h内依次完成上述实验。 结果 :PCV时峰压 (PIP)、平台压 (Pplat)明显低于 VCV时的 PIP、Pplat(P均 <0 .0 1) ,而 MPaw明显高于 VCV时的 MPaw(P <0 .0 1) ;在保持 MPaw相同时 ,氧合作用差异无统计学意义 (P >0 .0 5 ) ,患者均无气压伤。 结论 :PCV可以有效地控制 PIP、Pplat,并保证氧合 ,实现肺保护性通气。更多还原

【Abstract】 Objective: To assess the effects on respiratory mechanics and oxygenation in treatment of patients with acute respiratory distress syndrome (ARDS) by pressure control ventilation (PCV) and volume control ventilation (VCV). Methods: 20 patients with ARDS were treated by mechanical ventilation. Ten patients (group A) first took PCV, remaining constant tidal volume (V\-T) and mean airway pressure (MP aw ) respectively; while the other 10 patients (group B) took the reverse turn. SaO\-2 should keep stable for at least half an hour before monitoring index. Trials should be complete during 5hs. Results: Peak inspiration pressure (PIP) and plateau pressure(P plat ) in PCV were obviously lower than those in VCV (P all <0.01) , while MP aw was obviously higher than that in VCV(P<0.01). Keeping MP aw constant, blood oxygenation had no distinction between PCV and VCV (P>0.05). All patients showed no ventilator induced lung injury. Conclusion: PCV can effectively control PIP?P plat , ensure blood oxygenation and carry out lung protected ventilation.更多还原