【摘要】 目的　比较不同营养状况儿童血脂谱水平 ,为进一步开展成年期疾病早期预防提供理论依据。方法　对 447名儿童进行身高和体重测量 ,根据身高标准体重法分为正常、超重和肥胖 3组 ,采用HITACHI71 70型自动生化分析仪进行血脂谱水平测定。结果　肥胖儿童某油三脂 (TG)、载脂蛋白B(apoB)水平高于超重组和体重正常组儿童 ,而高密度脂蛋白 (HDL)、HDL/TC相反 ,差异有显著性 (P <0 .0 5) ;总胆固醇 (TC)、低密度脂蛋白胆固醇 (LDL -C)、载脂蛋白AI(apoAI)、脂蛋白 (a) [LP(a) ]、LDL -C/HDL -C各组间差异无显著性 (P >0 .0 5)。肥胖组儿童TG异常率明显高于超重组和体重正常组儿童 (P <0 .0 5)。儿童肥胖度与TG、apoB水平呈正相关 ,与HDL -C水平呈负相关。结论　儿童血脂谱水平异常检出率随肥胖度增加而上升 ,主要以TG异常为主更多还原

【Abstract】 Objective To compare the serum lipid levels of children under different nutrition status and provide a theoretical basis for further developping early prevention of adulthood diseases. Methods Totally 447 children participated in height and weight measurements were classified into obese, overweight and normal-weight groups according to the Weight for Height. Then their serum lipid levels were determined in the HITACHI 7170 Automatic Biochemistry Analysis System.Results Obese children had higher TG and apoB levels and lower HDL and HDL/TC levels compared with overweight or normal-weight children ( P <0.05). There was no significant difference in other lipid indices such as TC, LDL-C, apo AI, LP (a) and LDL-C/HDL-C among three groups ( P >0.05). The abnormal TG prevalence of obese children was obviously higher than that of overweight and normal-weight children ( P <0.05). Childhood obesity degree was correlated positively with the TG, apoB levels and negatively with the HDL-C level.Conclusions The prevalence of abnormal serum lipid levels increases along with obesity degree in children, especially the TG level.更多还原