【摘要】 目的 :研究紫荆牌消毒液对标准菌株及皮肤表面自然菌的杀菌效果和有关因素对杀菌效果的影响。方法 :通过载体定量杀灭试验观察不同时间、不同浓度紫荆牌消毒液对金黄色葡萄球菌、大肠杆菌和白色念珠菌的杀灭效果。结果 :紫荆牌消毒液 1/ 2稀释液作用 1m in可杀灭布片上 99.98%的金黄色葡萄球菌、大肠杆菌和 99.94%的白色念珠菌。 2 5 %和5 0 %小牛血清对该消毒液杀菌效果分别有中度和重度影响。该消毒液 1/ 3稀释液 ,作用 3 m in,对手皮肤表面自然菌的杀灭率为 95 .46%。 5 4℃放置 14d后 ,该消毒液对白色念珠菌杀灭率无明显下降。结论 :该消毒液对金黄色葡萄球菌、大肠杆菌和白色念珠菌杀灭效果良好 ,稳定性较好 ,但受有机物影响较大。更多还原

【Abstract】 Objective:In order to investigate the germicidal efficacy of the Zijing disinfectant to some standard bacterium and the natural bacterium on the skin surface and know the influence of the relative factors on the germicidal efficacy Methods:The carrier quantitative germicidal test was carried out on Staphylococcus aureus,Escherichia coli and Candida albicans in different exposed time,different dilute solution to the disinfectant Results:The killing rate of Staphylococcus aureus and Escherichia coli on the cloth strips exposed to its 1∶2 dilute solution for 1 min was 99 98% The killing rate of Candida albicans on the cloth strip exposed to its 1∶2 dilute solution for 1 min was 99 94% Presence of 25% and 50% of calf serum in the bacterial suspension contaminating the carrier had medium or significant influence on the germicidal efficacy of the disinfectant Its germicidal efficacy did not obviously change after storing at 54℃ for 14 days Its killing rate of natural bacterium on the surface of palm skin exposed to the 1∶3 dilute solution of this disinfectant for 3 min was 95 46% Conclusions:The efficacy of the disinfectant is good on Staphylococcus aureus ,Escherichia coli and Candida albicans The stability of the disinfectant is fine,but the influence of organic substance is significant to the germicidal efficacy更多还原