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EB病毒感染与口腔鳞状细胞癌关系的研究

The study of the relation between EH virus infection and oral squamous cell carcinoma

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【作者】 张建成陈瑞扬张洪杰程瑞芳任新宇

【Author】 ZHANG Jiancheng, CHEN Ruiyang , ZHANG Hongjie ,etal. Tianjin Stomatological Hospital, Tianjin 300041

【机构】 天津市口腔医院天津市口腔医院 300041300041300041

【摘要】 目的 探讨EB病毒感染与口腔鳞癌发生、发展的关系。方法 采用酶联免疫法检查234例住院患者血液中EBV抗体,对28例口腔癌病灶标本用多聚酶链反应技术(PCR)检测EBV基因组核抗原1区。结果234例住院患者的血液的EBV抗体阳性13例,阳性率5.55%。28例口腔癌病灶标本EBV核抗原1区阳性2例,阳性率7.1%(P>0.05)。结论 EBV感染与口腔鳞癌的发生无明显关系。

【Abstract】 Objective To study the relation between EB virus infection and the carcinogenesis and development of oral squamous cell carcinoma. Methods ELISA was used to check the EB virus antibody in 234 patient’s blood. We checked the gene group’s nucleus - antigen one area with PCR in 28 specimen of oral cancer. Results Out of 234 cases, 13 were EBV antibody positive, the positive rate was 5.55% . Out of 28 specimen of oral cancer, 2 were EBV antibody positive,the positive rate was 7.1% ( P >0.05). Conclusion There were no relationship between EBV infection and the oral squamous cell carcinoma.

【关键词】 EB病毒感染口腔鳞癌
【Key words】 EB virus Infection Oral squamous cell carcinoma
  • 【文献出处】 现代口腔医学杂志 ,Journal of Modern Stomatology , 编辑部邮箱 ,2003年04期
  • 【分类号】R739.8
  • 【下载频次】67
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