【摘要】 目的　观察 1,6-二磷酸果糖对新生儿窒息并发缺氧缺血性脑病 (HIE)的治疗作用。方法　将 2 0 2例HIE患儿随机分为 2组 ,治疗组给予 1,6-二磷酸果糖 ,对照组给予胞二磷胆碱治疗。结果　治疗组有效率为 96.2 % ,对照组有效率为 80 .6% ,两组比较有显著性差异(P <0 .0 5 )。结论　 1,6-二磷酸果糖治疗新生儿HIE有效率高 ,神经系统后遗症少 ,且无明显的副作用更多还原

【Abstract】 Objective It is to evaluate the effect of fructose-1, 6-diphosphate on hypoxic ischemic encephalopathy (HIE) of asphyxia neonatorum. Methods 202 infants with HIE were divided into two groups at random. Treatment group were treated with fructose-1, 6-diphosphate and control group were treated with citicoline. Results Effective rate of treatment group was 96.2% and that of control group was 80.6%. There was significantly difference betweem two groups (P<0.05). Conclusion With high effective rate, seldom sequela of nervous system and without obvious side effect, fructose-1, 6-diphosphate is effective on HIE of asphyxia neonatorum.更多还原