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电针和补阳还五汤治疗大鼠坐骨神经损伤的比较研究

Comparative experimental study on treatment of rat’s injured sciatic nerve with electroacupuncture and Buyang Huanwu Decoction

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【作者】 邵水金单宝枝姜俊严振国

【Author】 SHAO Shui Jin,SHAN Bao Zhi,JIANG Jun,YAN Zhen Guo (Department of Anatomy, Shanghai University of Traditional Chinese Medicine, Shanghai 200032,China)

【机构】 上海中医药大学解剖学教研室上海中医药大学解剖学教研室 上海200032上海200032上海200032

【摘要】 目的 研究电针、补阳还五汤对大鼠坐骨神经损伤后的再生作用。方法 采用手术造成大鼠坐骨神经损伤模型 ,电针、补阳还五汤治疗 ,进行神经电生理和HRP追踪观察。结果 电针组、补阳还五汤组的神经传导速度和诱发动作电位振幅恢复率高、脊髓前角和脊神经节标记细胞数多 ,与西药组、空白组比较有显著性差异 ,其中电针组优于补阳还五汤组。结论 电针、补阳还五汤均能更好地促进神经早期的功能恢复 ,是一种促进周围神经损伤后神经再生的有效手段

【Abstract】 Objective To study the effect of the electroacupuncture and Buyang Huanwu Decoction(BYHWD) on the regeneration of the rat’s injured sciatic nerve. Methods Rat’s sciatic nerve injury model was made by operation. The rats were treated with electroacupuncture or BYHWD and their nerve electro physiological indices and histological changes tested by HRP were observed. Results It was demonstrated that the recovery ratios of nerve conduction velocity and muscle evoked action potential of the group treated with electroacupuncture and the group treated with BYHWD were higher than those of the group treated with western medicine or the group without treatment. The differences were significant. The labeling cells in anterior horn of spinal marrow and spinal ganglion of the group treated with electroacupuncture and the group treated with BYHWD were more abundant than those of the group treated with western medicine or the group without treatment. The differences were significant. The effect of electroacupuncture was better than that of the BYHWD. Conclusion It suggests that both electroacupuncture therapy and BYHWD can promote the recovery of the function in early stage of injured nerve, and they are effective methods for promoting the regeneration of injured peripheral nerve.

【基金】 国家中医药管理局青年基金资助项目 (97Y0 0 8)
  • 【文献出处】 中西医结合学报 ,Journal of Chinese Integrative Medicine , 编辑部邮箱 ,2003年01期
  • 【分类号】R277.7
  • 【被引频次】11
  • 【下载频次】151
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