节点文献
160例成人HIV感染者/AIDS患者机会性感染与CD4+之间关系分析
Analysis of the incidence of opportunistic infections in relation with the change of CD4+ lymphocyte count in people living with HIV/AIDS.
【摘要】 目的 分析中国成人艾滋病病毒 (HIV)感染者 /艾滋病 (AIDS)患者机会性感染发生的频率与CD+4 细胞数之间的关系。方法 对 1990~ 2 0 0 1在北京佑安医院就诊的 160例成人HIV感染者 /AIDS患者CD+4 、CD+8进行跟踪分析。结果 ( 1)CD+4 >5 0 0个 / μl 66人次 ( 12 7% ) ,CD+4 为 2 0 0个 / μl~ 5 0 0个 / μl 2 12人次 ( 41 1% ) ,CD+4 <2 0 0个 / μl 2 3 4人次 ( 45 3 % )。在CD+4 <个 2 0 0 / μl中 ,CD+4 <10 0个 / μl 12 8人次 ( 2 4 8% ) ,CD+4 <5 0个 / μl 89人次( 17 2 % )。 ( 2 )CD+4 >2 0 0个 / μl时 ,共发生机会性感染 3 3人次 ( 15 6% )。CD+4 <2 0 0个 / μl时 ,共发生机会性感染170人次 ( 72 6% ) ,CD+4 为 10 0个 / μl~ 2 0 0个 / μl之间发生机会性感染 42人次 ( 3 9 6% ) ,CD+4 <10 0个 / μl发生机会性感染 12 8人次 ( 98 4% ) ,其中CD+4 <5 0个 / μl发生机会性感染 87人次 ( 97 8% )。 结论 中国成人HIV感染者 /AIDS患者在CD+4 >2 0 0个 / μl时机会性感染出现频率较少 ,CD+4 <2 0 0个 / μl时机会性感染的频率明显增加 ;CD+4 <10 0个 / μl和 <5 0个 / μl时 ,感染率约为 10 0 %。
【Abstract】 Objective To explore the change of CD + 4 lymphocyte count in relation with the incidence of opportunistic infections(OIS)in people living with HIV/AIDS.Method One hundred and sixty HIV/AIDS cases were analyzed and followed up among those visiting our hospital in 1990-2001.Results (1)For all the 160 HIV/AIDS cases CD + and CD + 8 lymphocyte count was analysed in a total of 512 tests,of which CD + 4>500/μ1 was detected in 66 tests(12.7%),CD + 4=200-500/μl-in 212 tests(41.1%)and CD + 4<200/μl-in 234 tests(45.3%).For the cases with CD + 4<200/μl CD + 4<100/μl was found in 128 tests(24.8%),and CD + 4<50/μl-in 89 tests(17.2%).(2)As to the OIS incidence,33 episodes were recorded in the cases with CD + 4>200/μl(15.6%),while 170 episodes were found in the cases with CD + 4<200/μl(72.6%); 42 episodes of OIS were recorded in those with CD + 4 between 100 and 200/μl(39.6%),and OIS rose to 126(98.4%)and 87(97.8%)episodes respectively when CD + 4 dropped below 100/μl and 50/μl.Conclusion Very few OIS occurred in CD + 4>200/μl,and the incidence of OIS will be increased significantly in CD + 4>200/μl,especially in CD + 4<100/μl and<50/μl.
【Key words】 HIV/AIDS; Opportunistic infections; CD + 4 lymphocyte count;
- 【文献出处】 中国艾滋病性病 ,Journal for China AIDS/STD , 编辑部邮箱 ,2003年01期
- 【分类号】R512.91
- 【被引频次】63
- 【下载频次】350